What is Systematic Evolution of Ligands by Exponential Enrichment (SELEX)?
The Systematic Evolution of Ligands by Exponential Enrichment, commonly known as SELEX, is a method used to identify high-affinity ligands from a large pool of nucleic acid sequences. This technique involves iterative rounds of selection and amplification to evolve oligonucleotides with a high affinity for specific target molecules. SELEX is widely used in nanotechnology for creating aptamers that can bind to a variety of targets, including proteins, small molecules, and even cells.
