What Factors Influence Toxicokinetics of Nanoparticles?
Several factors influence the toxicokinetics of nanoparticles, including: - Size and Shape: Smaller nanoparticles can penetrate deeper into biological tissues. - Surface Charge: Positively charged nanoparticles may interact more readily with cell membranes. - Coating and Functionalization: Surface modifications can influence the biocompatibility and biodistribution of nanoparticles. - Solubility: Water-soluble nanoparticles are generally cleared more rapidly from the body.