What Are the Mechanisms of Organ Damage Due to Nanoparticles?
There are several mechanisms by which nanoparticles can cause organ damage:
Oxidative Stress: Reactive oxygen species (ROS) generated by nanoparticles can lead to cellular damage and inflammation. Inflammation: Nanoparticles can activate immune responses, leading to chronic inflammation and subsequent tissue damage. Cellular Uptake: Some nanoparticles can penetrate cell membranes, disrupting cellular functions and potentially causing apoptosis (programmed cell death). Bioaccumulation: Persistent nanoparticles can accumulate in organs, leading to long-term toxicity.
