What are the Mechanisms of Carcinogenicity in Nanomaterials?
Several mechanisms have been proposed to explain how nanomaterials could induce cancer:
DNA damage: Nanoparticles can interact with DNA directly or indirectly, causing mutations that lead to cancer. Oxidative stress: Nanomaterials can generate reactive oxygen species (ROS), which can damage cellular components, including DNA, proteins, and lipids. Chronic inflammation: Persistent exposure to certain nanomaterials can induce chronic inflammation, a known risk factor for cancer development.
