What are the Key Parameters Evaluated in In Vitro Studies?
Several parameters are evaluated in in vitro studies to determine the impact of nanomaterials. These include:
Cytotoxicity: Assessing cell viability and proliferation after exposure to nanomaterials. Genotoxicity: Evaluating DNA damage and potential mutagenic effects. Oxidative Stress: Measuring the generation of reactive oxygen species (ROS) and antioxidant response. Cellular Uptake: Determining the extent and mechanism of nanomaterial internalization by cells. Inflammatory Response: Assessing the production of inflammatory cytokines and other markers.