Several factors influence the extent of membrane damage caused by nanoparticles, such as:
1. Particle Size: Smaller nanoparticles can penetrate membranes more easily. 2. Surface Charge: Positively charged nanoparticles are more likely to interact with negatively charged cell membranes. 3. Surface Functionalization: Chemical modifications on the nanoparticle surface can affect how they interact with membranes.