What are the challenges of using Capillary Electrophoresis in Nanotechnology?
Despite its advantages, CE also presents some challenges when applied to nanotechnology:
Complex Sample Matrices: Nanomaterials often exist in complex matrices that can interfere with the separation process. Surface Interactions: Nanoparticles can interact with the capillary walls, affecting their migration and separation. Detection Sensitivity: Detecting and quantifying nanoparticles at very low concentrations can be challenging. Method Development: Developing robust CE methods for specific nanomaterials requires significant expertise and optimization.
