Despite their promising applications, there are several challenges associated with the use of nanopores:
1. Fabrication Precision: Achieving precise control over the size and shape of nanopores is technically challenging and often requires sophisticated equipment. 2. Material Compatibility: Not all materials are suitable for nanopore fabrication, and finding the right substrate can be a limiting factor. 3. Signal Noise: In sensing applications, distinguishing the target molecule's signal from background noise can be difficult, necessitating advanced signal processing techniques. 4. Scalability: Scaling up nanopore-based technologies for commercial use remains a significant hurdle.
