Achieving precise size separation of nanoparticles poses several challenges:
1. Aggregation: Nanoparticles tend to aggregate, which complicates separation. 2. Polydispersity: Synthesized nanoparticles often have a broad size distribution, requiring multiple separation steps. 3. Surface Chemistry: The surface properties of nanoparticles can affect their interaction with separation media, influencing the effectiveness of size separation.
