What are the Challenges in Measuring Size Distribution?
Measuring the size distribution of nanoparticles comes with several challenges:
Polydispersity: Nanoparticle samples often contain particles of various sizes, making it difficult to determine an accurate size distribution. Sample preparation: The process of preparing samples for measurement can sometimes alter the size distribution. Aggregation: Nanoparticles tend to aggregate, which can complicate the measurement process. Instrument limitations: Each technique has its own limitations in terms of resolution, sensitivity, and the range of sizes it can measure.
