What are the Challenges in Chemical Formulation at the Nanoscale?
One of the primary challenges is ensuring the stability of the nanoparticles. Nanoparticles tend to aggregate due to their high surface energy, which can negate their advantageous properties. Additionally, accurately characterizing and controlling the size, shape, and distribution of nanoparticles is complex. Safety and toxicity issues also arise, as the small size of nanoparticles allows them to interact with biological systems in unpredictable ways.