What are the Benefits of Using Nanoparticles in PDT?
Incorporating nanoparticles into PDT offers several advantages:
Improved Solubility: Many photosensitizers are hydrophobic and poorly soluble in water. Nanoparticles can enhance their solubility and bioavailability. Targeted Delivery: Functionalized nanoparticles can deliver photosensitizers directly to cancer cells, minimizing damage to healthy tissues. Controlled Release: Nanoparticles can be designed to release the photosensitizer in response to specific stimuli, such as pH or temperature changes in the tumor microenvironment. Enhanced Photostability: Encapsulation within nanoparticles can protect photosensitizers from photobleaching, maintaining their effectiveness during treatment.
