AAV vectors offer several advantages in the context of nanotechnology and gene therapy: 1. Safety: AAVs are non-pathogenic to humans and have a low immunogenic profile, reducing the risk of adverse reactions. 2. Long-term expression: They can mediate long-term expression of the therapeutic gene, which is crucial for chronic conditions. 3. Versatility: AAV vectors can transduce dividing and non-dividing cells, expanding their applicability. 4. Targeted delivery: Through capsid engineering, AAV vectors can be tailored to deliver genes specifically to certain cell types.
