Nanofiber scaffolds offer several advantages over traditional scaffolding materials. Their high surface area-to-volume ratio facilitates better cell attachment and proliferation. The interconnected porous structure of nanofibers allows for efficient nutrient and waste exchange, which is crucial for cell survival and growth. Additionally, nanofiber scaffolds can be engineered to closely mimic the natural ECM, providing an optimal environment for cells to thrive. The versatility in material choice and fabrication techniques also allows for the customization of scaffolds to meet specific application requirements.