Nanofiber scaffolds can be fabricated using several techniques, with electrospinning being the most common method. In electrospinning, a high-voltage electric field is applied to a polymer solution, causing it to eject a thin jet that solidifies into nanofibers upon solvent evaporation. Other fabrication methods include self-assembly, phase separation, and melt blowing. Each method offers distinct advantages and can be chosen based on the intended application and desired scaffold properties.