What are Some Challenges in Image Acquisition at the Nanoscale?
Despite the advanced techniques available, there are several challenges in image acquisition at the nanoscale:
- Sample Preparation: Preparing samples without altering their nanostructure is critical yet challenging. Contamination and damage can affect the accuracy of the imaging results.
- Resolution and Contrast: Achieving high resolution and contrast can be difficult, especially for complex or heterogeneous samples.
- Instrumentation and Cost: High-end imaging equipment is expensive and requires specialized training to operate effectively.
- Environmental Factors: Vibration, temperature fluctuations, and electromagnetic interference can adversely affect image quality.
