While the potential benefits of nanotechnology in medicine are immense, safety remains a critical concern. The small size and high reactivity of nanoparticles can pose risks, such as toxicity and unintended interactions with biological systems. Extensive research is ongoing to understand and mitigate these risks. Regulatory bodies like the FDA are developing guidelines to ensure the safe use of nanotechnology in medical applications. It is essential to conduct thorough preclinical and clinical trials to evaluate the safety and efficacy of nanotechnology-based treatments.