The release rate of ions from nanomaterials can be controlled by modifying the material's properties. For example: 1. Surface Coatings: Applying surface coatings such as polymers or bioactive glass can slow down the release rate by acting as a barrier. 2. Particle Size: Smaller particles have a higher surface area-to-volume ratio, which can increase the release rate. Conversely, larger particles release ions more slowly. 3. Chemical Composition: Altering the chemical composition of the nanomaterial can influence its dissolution rate and, consequently, the release of ions.