Selectivity can be achieved through various mechanisms:
Surface Functionalization: By attaching specific ligands or antibodies to the surface of nanoparticles, they can be directed to bind only to target cells or molecules. Size and Shape: The physical dimensions of nanoparticles can influence their interaction with biological systems. Certain sizes and shapes are more likely to penetrate specific cell types. Chemical Composition: The material itself can be designed to interact selectively with target molecules. For example, gold nanoparticles can be tuned to bind with particular proteins.