Enhanced contrast can be achieved using various methods, including:
1. Nanoparticles: Nanoparticles such as gold or silver are used as contrast agents due to their unique optical properties. They can enhance the contrast in imaging techniques like optical microscopy and electron microscopy.
2. Quantum Dots: Quantum dots are semiconductor nanocrystals that exhibit size-dependent optical properties. They are used in fluorescence imaging to provide brighter and more stable signals compared to traditional dyes.
3. Surface-Enhanced Raman Scattering (SERS): This technique uses metallic nanostructures to amplify the Raman scattering signal of molecules, providing highly sensitive and specific chemical information.
