Achieving high accuracy in nanotechnology involves the use of advanced instrumentation and rigorous calibration procedures. Instruments such as scanning tunneling microscopes (STM) and atomic force microscopes (AFM) provide atomic-level resolution, allowing researchers to visualize and manipulate individual atoms and molecules. Additionally, spectroscopic techniques like Raman spectroscopy and X-ray diffraction are used to probe the structural and chemical properties of nanomaterials with high precision. Calibration of these instruments is performed using standard reference materials and well-defined protocols to ensure that measurements are accurate and reproducible. Furthermore, computational tools and simulation models play a significant role in predicting the behavior of nanomaterials, guiding experimental design, and interpreting results.