How Does Targeting Specific Cells or Tissues Pose a Challenge?
The ability to accurately target specific cells or tissues is vital for the efficacy of nanotherapeutics. However, achieving this is difficult due to the heterogeneous nature of tissues and the complexity of biological barriers. The enhanced permeability and retention (EPR) effect, which is often leveraged for passive targeting, does not always work uniformly across different types of tumors or diseased tissues.
