Nanotechnology offers several advantages for the development and deployment of radiosensitizers. By leveraging nanomaterials, we can achieve better targeting of cancer cells, reduce side effects on healthy tissues, and enhance the overall effectiveness of the treatment. Nanoparticles can be designed to accumulate preferentially in tumor tissues through the enhanced permeability and retention (EPR) effect, ensuring that higher concentrations of the radiosensitizer reach the tumor site.