Nanopharmaceuticals work by utilizing the small size and large surface area of nanoparticles to improve drug solubility, bioavailability, and controlled release. For instance, nanoparticles can be designed to release their drug payload slowly over time, providing a sustained therapeutic effect. Additionally, the surface of nanoparticles can be modified with ligands that target specific cells or tissues, ensuring that the drug is delivered precisely where it is needed. This targeted delivery reduces side effects and enhances the treatment's overall efficacy.