How Do Nanoparticles Interact with the Humoral Immune System?
Nanoparticles can be designed to either evade or activate the humoral immune response, depending on the desired outcome. For instance, polyethylene glycol (PEG)ylation of nanoparticles can reduce recognition by antibodies and prolong circulation time. Conversely, nanoparticles can be functionalized with specific antigens to stimulate the production of targeted antibodies, a strategy often used in vaccine development.
