Yes, certain nanoparticle designs can evade the immune system. By modifying surface characteristics, such as coating nanoparticles with polyethylene glycol (PEG) or other biocompatible materials, researchers can create "stealth" nanoparticles that are less likely to be recognized and attacked by immune cells. These strategies can prolong the circulation time of nanoparticles in the bloodstream, enhancing their efficacy in drug delivery and other applications.
