While randomization has many advantages, it also comes with some challenges: 1. Unpredictability: The inherent unpredictability can make it difficult to precisely control the final properties of the material or device. 2. Complex Analysis: Analyzing and interpreting the results of randomized processes can be computationally intensive and complex. 3. Variability: There can be significant variability between different samples, which might not be desirable for certain applications requiring high uniformity.