lin zhang - Nanotechnology

Author Information

Lin Zhang is affiliated with the Center for Research on Reproduction and Women's Health at the University of Pennsylvania, Philadelphia, Pennsylvania, USA. Zhang's research primarily focuses on cancer genomics, cancer treatment methodologies, and the molecular mechanisms underlying cancer progression.

Research Contributions

Lin Zhang has made significant contributions to the field of cancer research, particularly in the areas of druggable genes, epigenetic regulation, and cancer cell signaling pathways. Notable works include systematic illumination of druggable genes in cancer genomes, exploration of metabolism-related gene signatures predicting prognosis for ovarian cancer, and targeting PAK4 to improve CAR-T immunotherapy for glioblastoma. Zhang's research also delves into the role of long non-coding RNAs in cancer and potential therapeutic targets, as evidenced by multiple publications on the topic.

Aliases

No aliases were provided for Lin Zhang.

Publication and Citation Metrics

Metric	Value
Citation Count	20521
h-index	58
Paper Count	116

Publications:

Systematic illumination of druggable genes in cancer genomes

DOI: 10.1016/j.celrep.2022.110400

Year: 2022

Abstract 1185: PRMT5 inhibition epigenetically regulates DNA damage response pathways in cancer cells and sensitizes to chemotherapy and PARP inhibition

DOI: 10.1158/1538-7445.AM2021-1185

Year: 2021

Exploration of a Metabolism-Related Gene Signature Predicting Prognosis for Ovarian Cancer

DOI: 10.21203/rs.3.rs-917465/v1

Year: 2021

Detection of Long Non-coding RNA Expression by Non-radioactive Northern Blots.

DOI: 10.1007/978-1-0716-1697-0_13

Year: 2021

Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma.

DOI: 10.1038/s43018-020-00147-8

Year: 2021

The Cancer Surfaceome Atlas integrates genomic, functional and drug response data to identify actionable targets.

DOI: 10.1038/s43018-021-00282-w

Year: 2021

Targeting the transcription cycle and RNA processing in cancer treatment.

DOI: 10.1016/j.coph.2021.04.001

Year: 2021

Characterization of Long Non-coding RNA Associated Proteins by RNA-Immunoprecipitation.

DOI: 10.1007/978-1-0716-1697-0_3

Year: 2021

Methods for the Study of Long Noncoding RNA in Cancer Cell Signaling.

DOI: 10.1007/978-1-0716-0759-6_7

Year: 2021

Systematic Pan-Cancer Characterization of Nuclear Receptors Identifies Potential Cancer Biomarkers and Therapeutic Targets

DOI: 10.1158/0008-5472.CAN-20-3458

Year: 2021

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