Drug delivery: - Nanotechnology

What is Nanotechnology in Drug Delivery?

Nanotechnology in drug delivery involves the use of nanoparticles and other nanomaterials to improve the delivery and efficacy of drugs. By manipulating materials at the nanoscale, scientists can enhance the bioavailability, targeting, and controlled release of therapeutic agents.

How do Nanoparticles Enhance Drug Delivery?

Nanoparticles can improve drug delivery by increasing the surface area for drug interaction, enhancing solubility, and enabling targeted delivery to specific tissues or cells. They can be engineered to bypass biological barriers, such as the blood-brain barrier, and release drugs in a controlled manner.

What are the Types of Nanoparticles Used?

Various types of nanoparticles are employed in drug delivery, including liposomes, polymeric nanoparticles, dendrimers, and metallic nanoparticles. Each type has unique properties that make it suitable for different therapeutic applications.

What are the Benefits of Nanotechnology in Drug Delivery?

Nanotechnology offers several advantages, including improved drug solubility, enhanced absorption, targeted delivery, reduced side effects, and the ability to deliver multiple drugs simultaneously. These benefits can lead to more effective treatments with fewer doses and better patient compliance.

How is Targeted Drug Delivery Achieved?

Targeted drug delivery is achieved through surface modification of nanoparticles with ligands that bind specifically to receptors on target cells. This ensures that the drug is delivered directly to the diseased cells, minimizing damage to healthy tissues. Techniques like active targeting and passive targeting are commonly used.

What are the Challenges in Nanotechnology-Based Drug Delivery?

Despite its potential, nanotechnology-based drug delivery faces challenges such as toxicity, stability, scalability, and regulatory hurdles. Ensuring the biocompatibility and safe clearance of nanoparticles from the body is crucial for clinical applications.

What are the Future Prospects?

The future of nanotechnology in drug delivery is promising, with ongoing research into personalized medicine, smart drug delivery systems, and nanorobots. Advances in this field could revolutionize the treatment of complex diseases, including cancer, neurological disorders, and infectious diseases.

Relevant Publications

Controlled Release of Molecules to Enhance Cell Survival and Regeneration.

Issue Release: 2025

O-carboxymethyl chitosan in biomedicine: A review.

Issue Release: 2024

NANOSUSPENSIONS: ENHANCING DRUG BIOAVAILABILITY THROUGH NANONIZATION.

Issue Release: 2024

In vitro and in silico approach towards antimicrobial and antioxidant behaviour of water-soluble chitosan dialdehyde biopolymers.

Issue Release: 2024

Fully flexible implantable neural probes for electrophysiology recording and controlled neurochemical modulation.

Issue Release: 2024

A Study on the Behavior of Smart Starch--poly(-isopropylacrylamide) Hybrid Microgels for Encapsulation of Methylene Blue.

Issue Release: 2024

In Vivo Ocular Pharmacokinetics and Toxicity of Siponimod in Albino Rabbits.

Issue Release: 2024

Chlorogenic acid/carboxymethyl chitosan nanoparticle-assisted biomultifunctional hyaluronic acid-based hydrogel scaffolds for burn skin repair.

Issue Release: 2024

MgSiO Fiber Membrane Scaffold with Triggered Drug Delivery for Osteosarcoma Synergetic Therapy and Bone Regeneration.

Issue Release: 2024

Considerations when prescribing opioid agonist therapies for people living with HIV.

Issue Release: 2024

The Gene Expression Landscape of Disease Genes.

Issue Release: 2024

Exosomes in Bone Cancer: Unveiling their Vital Role in Diagnosis, Prognosis, and Therapeutic Advancements.

Issue Release: 2024

Construction of mitochondrial-targeting nano-prodrug for enhanced Rhein delivery and treatment for osteoarthritis in vitro.

Issue Release: 2024

Fabrication of pH-responsive temozolomide (TMZ)-clacked tannic acid-altered zeolite imidazole nanoframeworks (ZIF-8) enhance anticancer activity and apoptosis induction in glioma cancer cells.

Issue Release: 2024

Interfacial-engineered living drugs with \"ON/OFF\" switching for oral delivery.

Issue Release: 2024

A Quality by Design Approach for Optimizing Solid Lipid Nanoparticles of Bedaquiline for Improved Product Performance.

Issue Release: 2024

Hydrazone-functionalized nanoscale covalent organic frameworks as a nanocarrier for pH-responsive drug delivery enhanced anticancer activity.

Issue Release: 2024

Impacts of polyethylene glycol (PEG) dispersity on protein adsorption, pharmacokinetics, and biodistribution of PEGylated gold nanoparticles.

Issue Release: 2024

The role and application of small extracellular vesicles in glioma.

Issue Release: 2024

Recent advances in gene delivery nanoplatforms based on spherical nucleic acids.

Issue Release: 2024

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