Nanoparticles offer several advantages over traditional chromogenic reagents: 1. Enhanced Sensitivity: Nanoparticles can exhibit pronounced color changes even at low concentrations of the target analyte. 2. Specificity: Functionalized nanoparticles can be designed to selectively interact with specific molecules, improving assay specificity. 3. Versatility: Different types of nanoparticles and surface modifications allow for a wide range of applications.