Why is Biotin-Streptavidin Linkage Important in Nanotechnology?
The biotin-streptavidin linkage is crucial in nanotechnology because it offers an extremely high affinity and specificity, with a dissociation constant (Kd) in the order of 10^-15 M. This makes it an ideal tool for creating highly stable and specific nanostructures. The strength and specificity of this interaction enable the controlled assembly of nanoparticles, nanowires, and other nanoscale devices.