What is Photoactivated Localization Microscopy (PALM)?
Photoactivated Localization Microscopy (PALM) is a super-resolution imaging technique that allows scientists to visualize structures at the nanoscale. This method overcomes the diffraction limit of conventional microscopy, offering a resolution down to 20-30 nanometers. PALM achieves this by utilizing photoactivatable fluorescent proteins that can be switched on and off, allowing individual molecules to be localized with high precision.
