What Factors Influence the Phagocytosis of Nanoparticles?
Several factors determine whether nanoparticles will be phagocytosed by immune cells:
Size: Typically, particles in the range of 20-200 nm are most likely to be phagocytosed. Shape: Spherical particles are more readily engulfed than rod-shaped or other non-spherical particles. Surface Chemistry: The presence of specific surface ligands or coatings can enhance or inhibit phagocytosis. Charge: Positively charged particles are more likely to interact with the negatively charged cell membranes.
