Several factors can influence protein binding to nanoparticles:
Surface Chemistry: The chemical composition and functional groups on the nanoparticle surface can dictate protein adsorption. Size and Shape: Nanoparticles of different sizes and shapes exhibit different binding affinities and protein corona compositions. Charge: The surface charge of nanoparticles can attract or repel proteins, affecting binding dynamics. Environmental Conditions: pH, temperature, and ionic strength of the solution can alter protein-nanoparticle interactions.
