Several factors can impact delivery efficiency, including:
1. Particle Size and Shape: The size and shape of nanoparticles can affect their ability to navigate biological barriers and be taken up by cells. 2. Surface Chemistry: The surface properties of nanoparticles, such as charge and hydrophobicity, influence their interaction with biological environments. 3. Targeting Mechanisms: The presence of targeting ligands on the nanoparticle surface can enhance the specificity and uptake by target cells or tissues. 4. Biodegradability: The rate at which nanoparticles degrade within the body impacts how long they can deliver their payloads effectively.
