Despite their potential, nanomedicines face several challenges. One of the primary concerns is toxicity. The long-term effects of nanoparticles on the human body are not fully understood, and there is a need for more research to ensure their safety. Another challenge is the regulatory landscape, as current regulations may not fully address the unique characteristics of nanomedicines. Additionally, the cost of developing and manufacturing nanomedicines can be high, which may limit their accessibility.