CRISPR-Cas9: A widely used technology that utilizes a guide RNA to locate the target DNA sequence and a Cas9 enzyme to cut the DNA at the desired location. TALENs (Transcription Activator-Like Effector Nucleases): Customizable proteins that bind to specific DNA sequences and create double-strand breaks to edit genes. ZFNs (Zinc Finger Nucleases): Engineered proteins that use zinc finger domains to recognize specific DNA sequences and introduce double-strand breaks.