1. Size and Scale: Understanding the nanoscale and how properties of materials change at this scale. 2. Quantum Mechanics: Fundamental principles that govern the behavior of particles at the nanoscale. 3. Self-Assembly: The process by which molecules spontaneously form ordered aggregates. 4. Nanofabrication: Techniques for constructing nanoscale structures, such as lithography and bottom-up fabrication. 5. Characterization Techniques: Methods like scanning electron microscopy (SEM) and atomic force microscopy (AFM) to study nanoscale materials.