What are the Common Methods of Chemical Conjugation?
Several methods are used for chemical conjugation in nanotechnology:
1. Covalent Bonding: This involves forming strong covalent bonds between the nanoparticle and the conjugated molecule. Techniques like click chemistry and cross-linking are popular. 2. Electrostatic Interactions: These involve weaker interactions based on the electrostatic attraction between charged molecules and nanoparticles. 3. Hydrophobic Interactions: These are used to conjugate molecules that are hydrophobic in nature, leveraging the hydrophobic regions of nanoparticles.