transdermal delivery

What are the Challenges in Transdermal Delivery?

Despite its advantages, transdermal delivery faces several challenges:
1. Skin Barrier: The stratum corneum is the primary barrier that limits drug penetration.
2. Drug Properties: Only drugs with appropriate molecular size, lipophilicity, and potency are suitable for transdermal delivery.
3. Nanocarrier Stability: Ensuring the stability of nanocarriers during storage and application can be difficult.

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