What Are the Challenges in Studying Renal Clearance of Nanomaterials?
One of the main challenges in studying renal clearance is the complexity of the kidney's filtration system. The glomerular filtration barrier is selective, making it difficult to predict how different nanomaterials will be filtered. Additionally, the interaction of nanomaterials with proteins and other biological molecules can affect their clearance. Advanced imaging and analytical techniques are required to accurately track and measure the clearance of nanomaterials.