Despite the advancements, there are several challenges in achieving precise particle size control:
1. Uniformity: Ensuring uniform particle size distribution remains a challenge. 2. Scalability: Techniques that work well in the lab may not be easily scalable for industrial production. 3. Stability: Nanoparticles tend to agglomerate, leading to changes in size and properties over time. 4. Cost: Some methods are expensive, limiting their feasibility for large-scale applications.