What are the Challenges in Nanotechnology-Based Combination Therapy?
Despite the promising advantages, several challenges need to be addressed:
Toxicity of Nanomaterials: Some nanomaterials themselves could pose toxicity issues, necessitating thorough biocompatibility studies. Complex Manufacturing: The production of multifunctional nanocarriers with precise control over drug loading and release profiles is technically challenging and expensive. Regulatory Hurdles: Regulatory agencies require extensive safety and efficacy data before approving nanotechnology-based therapies, which can prolong the development timeline. Stability and Storage: Ensuring the stability of nanocarriers during storage and in biological environments remains a critical issue.
