Despite its potential, nanoscale detection faces several challenges:
1. Reproducibility: Ensuring consistent performance across different batches of nanomaterials. 2. Stability: Long-term stability of nanomaterials in varying environmental conditions. 3. Scalability: Difficulty in mass-producing nanoscale sensors at a low cost. 4. Regulatory Issues: Lack of standardized protocols and regulations for the use of nanomaterials in detection systems.