Despite its benefits, green synthesis faces several challenges:
Scalability: Producing nanoparticles on a large scale while maintaining uniformity is difficult. Standardization: There is a lack of standardized methods for green synthesis, leading to variability in nanoparticle properties. Purification: Isolating and purifying nanoparticles from biological matrices can be complex. Stability: Ensuring the long-term stability of green-synthesized nanoparticles remains a concern.