What Are the Challenges in Gene Delivery Using Nanotechnology?
Despite the potential, several challenges need to be addressed:
1. Efficiency: Ensuring that sufficient genetic material reaches the target cells and expresses the desired gene. 2. Specificity: Targeting only the intended cells or tissues to minimize off-target effects. 3. Safety: Reducing immunogenicity and toxicity to avoid adverse reactions. 4. Stability: Maintaining the stability of the genetic material during delivery and ensuring its efficient release within the target cells.
