Despite their potential, the development of SRNPs faces several challenges: - Biocompatibility: Ensuring that SRNPs are safe and non-toxic to the human body is crucial for medical applications. - Stability: SRNPs must remain stable under physiological conditions to be effective. - Targeting accuracy: Achieving precise targeting to specific cells or tissues is essential for minimizing side effects. - Scalability: Producing SRNPs on a large scale while maintaining their quality and functionality can be difficult.