Despite their potential, dendrimers face several challenges that need to be addressed:
Synthesis Complexity: The synthesis of dendrimers, especially large ones, can be complex and time-consuming. Toxicity: Some dendrimers, particularly those with cationic surface groups, can be toxic to cells, necessitating careful design and testing. Cost: The production of dendrimers can be expensive, limiting their widespread use in commercial applications. Scalability: Scaling up the production of dendrimers while maintaining their quality and consistency is a significant challenge.