What Are the Challenges in Achieving Lower Detection Limits?
Achieving lower detection limits involves several challenges:
1. Background Noise: Reducing background noise to distinguish the signal from the substance of interest is a significant challenge. 2. Sample Preparation: Proper sample preparation is crucial to avoid contamination and ensure accurate measurements. 3. Instrument Sensitivity: Enhancing the sensitivity of instruments without compromising their specificity and accuracy can be difficult. 4. Reproducibility: Ensuring that detection limits are reproducible across different samples and conditions is essential for reliable measurements.
