Nano LC offers several advantages over traditional liquid chromatography techniques:
1. High Sensitivity: The small sample volumes and the use of nanoscale materials provide exceptional sensitivity, making it possible to detect trace amounts of compounds. 2. Enhanced Resolution: The increased surface area of the nanomaterials improves the separation resolution, allowing for better discrimination between closely related compounds. 3. Reduced Sample Consumption: Nano LC requires significantly smaller sample volumes, which is particularly beneficial when dealing with limited or precious samples. 4. Improved Efficiency: The reduced column dimensions and the use of high-efficiency packing materials lead to faster and more efficient separations.